Study finds no connection between the Covid vaccinations used in India and the risk of heart attack

An observational study that underlines the preventive benefit of the shots found no link between the Covid-19 vaccinations used in India -- Covishield and Covaxin -- and a rise in the incidence of heart attacks.

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The study, which was just released in the journal PLOS One, examined the effect of COVID-19 vaccination on heart attack or acute myocardial infarction (AMI)-related death.

Data from 1,578 patients hospitalised to Delhi's G B Pant Hospital between August 2021 and August 2022 were used in the retrospective analysis. 1,086 people (68.8%) received the COVID-19 vaccine, compared to 492 (31.2%), who did not.

1,047 (96% of the vaccinated group) had gotten two doses of the vaccine, compared to 39 (4%) who had only received one.

Mortality rates were lower among people who had received immunisations

According to the report, vaccines used in India are secure. In India, there was no connection between vaccination and heart attacks. Mohit Gupta, the study's principal investigator from G B Pant Hospital, told PTI that the study actually showed that those who had received vaccinations had lower mortality rates following heart attacks.

The majority of COVID-19 vaccination AEs has been moderate, temporary, and self-limiting. However, issues have been brought up regarding these vaccinations' negative cardiovascular side effects.

The scientists warned that any adverse effect can have disastrous consequences, particularly in big, densely populated countries like India.

Data on the patient's vaccination history, including specifics on the type of vaccine received, the day of immunisation, and any side effects, was gathered for all of the enrolled patients.

No solid evidence linking the COVID-19 vaccination to heart attacks.

The study did not reveal any distinct clustering of AMI (Acute myocardial infarction ) at any given time after immunisation, the researchers discovered, indicating that there was no conclusive link between the COVID-19 vaccine and heart attacks.

At the 30-day follow-up, 201 (12.7%) patients had all-cause mortality, with the adjusted mortality chances being markedly lower in the immunised group.

Similar to this, the AMI group that had received the vaccination showed lower mortality probabilities at six months' follow-up than the non-vaccinated group.

The study found that COVID-19 vaccinations reduced all-cause mortality at 30 days and six months after AMI.

Increased age, diabetes , and Smoking served as risk factors

The researchers did note that there was a larger risk of 30-day death with increased age, diabetes, and smoking.

According to the study's findings, the risk of all-cause mortality within 30 days and six months was considerably lower in the vaccinated patients than in the general population.

Covid vaccine found out to be protective in reducing all-cause mortality

The COVID-19 vaccine was found to be not only safe but also possess a protective effect in terms of reducing all-cause mortality both in the short term and at six months of follow-up, according to the study's authors. This study is the first to be carried out among a larger population of AMI patients.

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